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Welcome to the New England Journal of Medicine audio summary for the week of October 2nd, 2008. I'm Dr. Lise Johnson. This week's issue featuresThis summary covers the issue of October 2, 2008. Featured arearticles on maraviroc for previously treated patients with R5 HIV-1 infection, subgroup analyses of maraviroc in previously treated R5 HIV-1 infection, toll-like receptor 3 and geographic atrophy in age-related macular degeneration, continuous glucose monitoring and intensive treatment of type 1 diabetes, and lethal injection and the Constitution; review articles on autosomal dominant polycystic kidney disease and on hepatitis B virus infection; a Clinical Problem-Solving article describing variations on a theme; and Perspective articles on harnessing employer inventiveness in U.S. health care reform, on executive physicals, and on the statins in preventive cardiology.